Current Funded Projects

Role of CXCR3 Agonists in the Generation of Autoreactive B cells in Scleroderma Patients

Hospital for Special Surgery
Yale School of Medicine

Franck Barrat, PhD Senior Scientist
Eric Meffre, PhD Associate Professor of Immunobiology and Medicine

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Defining Novel Autoantibodies that are Probes of Cancer-Induced Autoimmunity and Risk in Scleroderma

Johns Hopkins University School of Medicine

Livia Casciola-Rosen, PhD Professor of Medicine
Ami Shah, MD, MHS Associate Professor of Medicine

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Gene Regulatory Mechanisms in Scleroderma

Stanford University School of Medicine

Howard Chang, MD, PhD Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics, Director, NIH Center of Excellence in Genomic Science; Investigator, Howard Hughes Medical Institute

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Epigenetics of Sex Differences in Scleroderma

Stanford University School of Medicine

Howard Chang, MD, PhD Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics, Director, NIH Center of Excellence in Genomic Science; Investigator, Howard Hughes Medical Institute

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Scleroderma Twin Study

Stanford University School of Medicine

Howard Chang, MD, PhD Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics, Director, NIH Center of Excellence in Genomic Science; Investigator, Howard Hughes Medical Institute

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Stanford Scleroderma Center of Excellence

Stanford University School of Medicine

Lorinda Chung, MD, MS Associate Professor of Medicine
David Fiorentino, MD, PhD Associate Professor of Dermatology

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Northern California Scleroderma Research Consortium

Stanford University School of Medicine
University of California, San Francisco

Lorinda Chung, MD, MS Associate Professor of Medicine
Paul Wolters, MD Professor of Medicine

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Investigating X-chromosome-related Differences in Scleroderma

Johns Hopkins University School of Medicine

Erika Darrah, PhD Assistant Professor in Medicine

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Naturally Presented Topoisomerase Epitopes in Scleroderma Patients with HLA-DPB1’13:01

Johns Hopkins University School of Medicine

Erika Darrah, PhD Assistant Professor in Medicine
Eleni Tiniakou, MD Instructor of Medicine

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Interrogation of the Pathogenesis of Stiff Skin Syndrome: A Congenital Form of Scleroderma

Johns Hopkins University School of Medicine

Hal Dietz, MD Victor A. McKusick Professor of Genetics and Medicine; Professor of Pediatrics; Investigator, Howard Hughes Medical Institute

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Assessment of the Complement Cascade as a Novel Biomarker, Genetic Risk Factor, and Treatment Target for Scleroderma-Associated Pulmonary Arterial Hypertension

University of Rochester School of Medicine and Dentistry

Benjamin Korman, MD Assistant Professor of Medicine

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Measuring and Objectively Characterizing Patterns of Gastrointestinal Dysmotility in Scleroderma

Johns Hopkins University School of Medicine

Zsuzsanna McMahan, MD Assistant Professor of Medicine

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Identifying Autoantigens in Severe Gastrointestinal Disease

Johns Hopkins University School of Medicine

Zsuzsanna McMahan, MD Assistant Professor of Medicine
Jay Pasricha, MD Director of the Johns Hopkins Center for Neurogastroenterology; Professor of Medicine

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Macrophage-Stromal Cell Interactions in Tissue Homeostasis and Fibrosis

Yale School of Medicine

Ruslan Medzhitov, PhD Sterling Professor of Immunobiology; Investigator, Howard Hughes Medical Institute

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Identification of Novel Pathogenic Genes in Juvenile Systemic Sclerosis

Pittsburgh Children’s Hospital
Seattle Children’s Research Institute

Kathryn Torok, MD Assistant Professor of Medicine
Anne Stevens, MD, PhD Professor of Medicine

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Immune Checkpoint Inhibitors as Antifibrotic Therapy for Scleroderma

Stanford University School of Medicine

Gerlinde Wernig, MD Assistant Professor of Pathology

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Molecular Subsets, Integrative Genomics and Tissue Models of Scleroderma

Geisel School of Medicine at Dartmouth

Michael L. Whitfield, PhD Interim Chair and Professor of Biomedical Data Science; Professor of Molecular and Systems

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Johns Hopkins Scleroderma Center of Excellence

Johns Hopkins University School of Medicine

Fredrick Wigley, MD Director, the Johns Hopkins Scleroderma Center; Martha McCrory Professor of Medicine

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Genome Research in African American Scleroderma Patients (The GRASP Project)

Johns Hopkins University School of Medicine
University of California, San Francisco
National Human Genome Research Institute

Fredrick Wigley, MD Director, the Johns Hopkins Scleroderma Center; Martha McCrory Professor of Medicine
Francesco Boin, MD Director, UCSF Scleroderma Clinic; Professor of Medicine

In collaboration with
Dan Kastner, MD, PhD Scientific Director of the Intramural Program at the National Human Genome Research Institute

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Scleroderma Lung Disease Trajectory Modeling Project

Johns Hopkins University School of Medicine

Scott Zeger, PhD Professor of Biostatistics
Antony Rosen, MD Vice Dean for Research; Mary Betty Stevens Professor of Medicine
Laura Hummers, MD, MPH Clinical Director, Division of Rheumatology, Associate Professor of Medicine
Fredrick Wigley, MD Director, the Johns Hopkins Scleroderma Center; Martha McCrory Professor of Medicine
Ami Shah, MD, MHS Associate Professor of Medicine

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Past Funded Projects

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