Role of CXCR3 Agonists in the Generation of Autoreactive B cells in Scleroderma Patients

Hospital for Special Surgery
Yale School of Medicine

Franck Barrat, PhD Senior Scientist
Eric Meffre, PhD Associate Professor of Immunobiology and Medicine

Cancer Detection Strategies in Patients with Scleroderma

Johns Hopkins University School of Medicine

Livia Casciola-Rosen, PhD Professor of Medicine
Ami Shah, MD, MHS Associate Professor of Medicine

Gene Regulatory Mechanisms in Scleroderma

Stanford University School of Medicine
Howard Hughes Medical Institute

Howard Chang, MD, PhD Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics, Director, NIH Center of Excellence in Genomic Science; Investigator, Howard Hughes Medical Institute; Director, Center for Personal Dynamic Regulomes, Professor of Dermatology and of Genetics 

Epigenetics of Sex Differences in Scleroderma

Stanford University School of Medicine
Howard Hughes Medical Institute

Howard Chang, MD, PhD Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics, Director, NIH Center of Excellence in Genomic Science; Investigator, Howard Hughes Medical Institute; Director, Center for Personal Dynamic Regulomes, Professor of Dermatology and of Genetics 

Scleroderma Twin Study

Stanford University School of Medicine

Howard Chang, MD, PhD Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics, Director, NIH Center of Excellence in Genomic Science; Investigator, Howard Hughes Medical Institute

Establishing a Spatially–Integrated Transcriptomic, Epigenomic, and Histologic Signature of Fibrosis in Systemic Sclerosis

Stanford University School of Medicine

Michael Longaker, MD Deane P. and Louise Mitchell Professor in the School of Medicine and Professor, by courtesy, of Materials Science and Engineering
Howard Chang, MD, PhD Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics, Director, NIH Center of Excellence in Genomic Science; Investigator, Howard Hughes Medical Institute

Stanford Scleroderma Center of Excellence

Stanford University School of Medicine

Lorinda Chung, MD, MS Associate Professor of Medicine

Northern California Scleroderma Research Consortium

Stanford University School of Medicine
University of California, San Francisco

Lorinda Chung, MD, MS Associate Professor of Medicine
Paul Wolters, MD Professor of Medicine

Naturally Presented Topoisomerase Epitopes in Scleroderma Patients with HLA-DPB1’13:01

Johns Hopkins University School of Medicine

Erika Darrah, PhD Assistant Professor of Medicine
Eleni Tiniakou, MD Assistant Professor of Medicine

Assessment of the Complement Cascade as a Novel Biomarker, Genetic Risk Factor, and Treatment Target for Scleroderma-Associated Pulmonary Arterial Hypertension

University of Rochester School of Medicine and Dentistry

Benjamin Korman, MD Assistant Professor of Medicine

Measuring and Objectively Characterizing Patterns of Gastrointestinal Dysmotility in Scleroderma

Johns Hopkins University School of Medicine

Zsuzsanna McMahan, MD Assistant Professor of Medicine

Discovery of Novel Autoantigens in Scleroderma Patients with Gastrointestinal Dysmotility

Johns Hopkins University School of Medicine

Zsuzsanna McMahan, MD Assistant Professor of Medicine
Jay Pasricha, MD Director of the Johns Hopkins Center for Neurogastroenterology; Professor of Medicine

Macrophage-Stromal Cell Interactions in Tissue Homeostasis and Fibrosis

Yale School of Medicine
Howard Hughes Medical Institute

Ruslan Medzhitov, PhD Sterling Professor of Immunobiology; Investigator, Howard Hughes Medical Institute

Identification of Novel Pathogenic Genes in Juvenile Systemic Sclerosis

Pittsburgh Children’s Hospital
Seattle Children’s Research Institute

Kathryn Torok, MD Associate Professor of Medicine
Anne Stevens, MD, PhD Professor of Medicine

Immune Checkpoint Inhibitors as Antifibrotic Therapy for Scleroderma

Stanford University School of Medicine

Gerlinde Wernig, MD Assistant Professor of Pathology

Molecular Subsets, Integrative Genomics and Tissue Models of Scleroderma

Geisel School of Medicine at Dartmouth

Michael L. Whitfield, PhD Chair and Professor of Biomedical Data Science; Professor of Molecular and Systems

Johns Hopkins Scleroderma Center of Excellence

Johns Hopkins University School of Medicine

Fredrick Wigley, MD Director, the Johns Hopkins Scleroderma Center and Associate Director, Division of Rheumatology; Martha McCrory Professor of Medicine

Genome Research in African American Scleroderma Patients (The GRASP Project)

Cedars-Sinai
Johns Hopkins University School of Medicine
National Human Genome Research Institute
National Institute of Arthritis & Musculoskeletal Disease

Fredrick Wigley, MD Director, the Johns Hopkins Scleroderma Center and Associate Director, Division of Rheumatology
Francesco Boin, MD Director, Rheumatology Division, Kao Autoimmunity Institute

In collaboration with
Dan Kastner, MD, PhD Scientific Director of the Intramural Program at the National Human Genome Research Institute
Pravitt Gourh, MD Head, Scleroderma Genomics and Health Disparities Unit
Adjunct Investigator, National Institute on Minority Health and Health Disparities (NIMHD)

Scleroderma Lung Disease Trajectory Modeling Project

Johns Hopkins University School of Medicine

Scott Zeger, PhD Professor of Biostatistics
Antony Rosen, MD Vice Dean for Research; Mary Betty Stevens Professor of Medicine
Laura Hummers, MD, MPH Clinical Director, Division of Rheumatology, Associate Professor of Medicine
Fredrick Wigley, MD Director, the Johns Hopkins Scleroderma Center and Associate Director, Division of Rheumatology; Martha McCrory Professor of Medicine
Ami Shah, MD, MHS Associate Professor of Medicine

Multi-omic Profiling of Interstitial Lung Disease in Systemic Sclerosis

Paul Wolters, MD Professor of Medicine, UC San Francisco
Gerlinde Wernig, MD Assistant Professor of Pathology, Stanford University
Howard Chang, MD, PhD Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics, Director, NIH Center of Excellence in Genomic Science; Investigator, Howard Hughes Medical Institute