This list is of projects completed since 2020. We are continually adding more history of funded projects since we started supporting research in 1987—check back soon for more.
Elucidating the Role of Dynamic X Inactivation Maintenance in the Pathogenesis of SSc
Nikhil Jiwrajka
University of Pennsylvania — Fellow, Department of Rheumatology
Northern California Scleroderma Research Consortium
Stanford University School of Medicine
University of California, San Francisco
Lorinda Chung, MD, MS Professor of Medicine
Paul Wolters, MD Professor of Medicine
Investigating X-chromosome-related Differences in Scleroderma
Johns Hopkins University School of Medicine
Erika Darrah, PhD Assistant Professor in Medicine
Interrogation of the Pathogenesis of Stiff Skin Syndrome: A Congenital Form of Scleroderma
Johns Hopkins University School of Medicine
Hal Dietz, MD Victor A. McKusick Professor of Genetics and Medicine; Professor of Pediatrics; Investigator, Howard Hughes Medical Institute
Novel Therapeutic Vulnerabilities in Systemic Sclerosis and Fibrosis
Johns Hopkins University School of Medicine
Hal Dietz, MD Victor A. McKusick Professor of Genetics and Medicine; Professor of Pediatrics; Investigator, Howard Hughes Medical Institute
Discovery of Novel Autoantigens in Scleroderma Patients with Gastrointestinal Dysmotility
Johns Hopkins University School of Medicine
Zsuzsanna McMahan, MD Assistant Professor of Medicine
Jay Pasricha, MD Director of the Johns Hopkins Center for Neurogastroenterology; Professor of Medicine
Cancer Detection Strategies in Patients with Scleroderma
Johns Hopkins University School of Medicine
Livia Casciola-Rosen, PhD Professor of Medicine
Ami Shah, MD, MHS Associate Professor of Medicine
Immune Checkpoint Inhibitors as Antifibrotic Therapy for Scleroderma
Stanford University School of Medicine
Gerlinde Wernig, MD Assistant Professor of Pathology
Johns Hopkins Scleroderma Center of Excellence
Johns Hopkins University School of Medicine
Fredrick Wigley, MD Director, the Johns Hopkins Scleroderma Center and Associate Director, Division of Rheumatology; Martha McCrory Professor of Medicine
Laura Hummers, MD, MPH Clinical Director, Division of Rheumatology, Associate Professor of Medicine
Ami Shah, MD, MHS Associate Professor of Medicine
POL3-specific CD8+ T Cells as the Link Between Scleroderma and Anti-tumor Immune Responses
Johns Hopkins University School of Medicine
Erika Darrah, PhD Assistant Professor of Medicine
Eleni Tiniakou, MD Assistant Professor of Medicine
Role of CXCL4-induced TLR9 Defects Promote the Production of Autoreactive B-cells in Scleroderma
Hospital for Special Surgery
Stanford University School of Medicine
Franck Barrat, PhD Senior Scientist
Eric Meffre, PhD Professor of Medicine – Immunology & Rheumatology
Stanford Scleroderma Center of Excellence
Stanford University School of Medicine
Lorinda Chung, MD, MS Professor of Medicine
Understanding the Biological Basis of Enteric Nervous System Dysfunction in Systemic Sclerosis
Johns Hopkins University School of Medicine
Jay Pasricha, MD Director of the Johns Hopkins Center for Neurogastroenterology; Professor of Medicine
Subhash Kulkarni, MS, PhD Assistant Professor of Medicine
Assessment of the Complement Cascade as a Novel Biomarker, Genetic Risk Factor, and Treatment Target for Scleroderma-Associated Pulmonary Arterial Hypertension
University of Rochester School of Medicine and Dentistry
Benjamin Korman, MD Assistant Professor of Medicine
Measuring and Objectively Characterizing Patterns of Gastrointestinal Dysmotility in Scleroderma
Johns Hopkins University School of Medicine
Zsuzsanna McMahan, MD Assistant Professor of Medicine
Next Generation Proteomics to Identify Novel Immune Targets for Scleroderma
Gerlinde Wernig, MD
Stanford University — Assistant Professor of Pathology
Genome Research in African American Scleroderma Patients (The GRASP Project)
Fredrick Wigley, MD
Johns Hopkins University School of Medicine — Director, the Johns Hopkins Scleroderma Center and Associate Director, Division of Rheumatology
Francesco Boin, MD
Cedars-Sinai — Director, Rheumatology Division, Kao Autoimmunity Institute
In collaboration with
Dan Kastner, MD, PhD
National Human Genome Research Institute — Scientific Director of the Intramural Program
Charles Rotimi, PhD
National Human Genome Research Institute
Pravit Gourh, MD
National Institute of Arthritis and Musculoskeletal and Skin Diseases — MD Head, Scleroderma Genomics and Health Disparities Unit
National Institute on Minority Health and Health Disparities — Adjunct Investigator
Naturally Presented Topoisomerase Epitopes in Scleroderma Patients with HLA-DPB1*13:01
Erika Darrah, PhD
Johns Hopkins University School of Medicine — Assistant Professor of Medicine
Eleni Tiniakou, MD
Johns Hopkins University School of Medicine — Assistant Professor of Medicine
Genomics of Calcinosis
Lorinda Chung, MD, MS
Stanford University School of Medicine — Professor of Medicine
In collaboration with
Pravitt Gourh, MD
National Institute of Arthritis and Musculoskeletal and Skin Diseases — MD Head, Scleroderma Genomics and Health Disparities Unit
National Institute on Minority Health and Health Disparities — Adjunct Investigator
Examining Mechanisms of Autonomic Nervous System Dysfunction and GI Disease in Scleroderma
Zsuzsanna McMahan, MD of the UTHealth Houston McGovern School of Medicine
Gabsang Lee of the Johns Hopkins University School of Medicine
SRF and SCTC Jointly Funded Projects
Systemic Sclerosis Interstitial Lung Disease Progression (SILPRO) Score: Development of a Disease-Specific Model to Define Progression of SSc-ILD
Cosimo Bruni, MD and Oliver Distler, MD of the University Hospital Zurich
