Regulation of Inflammation and IFN-I response in the Fibrotic Skin Environment

Franck Barrat, PhD
Hospital for Special Surgery — Senior Scientist

Characterization of Somatic Mutations in Scleroderma

David Beck, MD, PhD of New York University
Shervin Assassi, MD, MS of the UTHealth Houston McGovern School of Medicine

Gene Regulatory Mechanisms in Scleroderma

Howard Chang, MD, PhD
Stanford University School of Medicine — Professor of Dermatology and of Genetics, Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics
Howard Hughes Medical Institute — Investigator
NIH Center of Excellence in Genomic Science: Center for Personal Dynamic Regulome — Director

Epigenetics of Sex Differences in Scleroderma

Howard Chang, MD, PhD
Stanford University School of Medicine — Professor of Dermatology and of Genetics, Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics
Howard Hughes Medical Institute — Investigator
NIH Center of Excellence in Genomic Science: Center for Personal Dynamic Regulome — Director

Scleroderma Twin Study

Howard Chang, MD, PhD
Stanford University School of Medicine — Professor of Dermatology and of Genetics, Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics
Howard Hughes Medical Institute — Investigator
NIH Center of Excellence in Genomic Science: Center for Personal Dynamic Regulome — Director

Cell Surface GlycoRNAs in Autoimmunity

Ryan Flynn, MD, PhD
Boston Children’s Hospital —Assistant Professor
Harvard University — Assistant Professor, Stem Cell and Regenerative Biology

In collaboration with
Livia Casciola-Rosen, PhD
Johns Hopkins University School of Medicine — Professor of Medicine
Antony Rosen, MBChB, MS
Johns Hopkins University School of Medicine — Vice Dean for Research

Elucidating the Role of Dynamic X Inactivation Maintenance in the Pathogenesis of SSc

Nikhil Jiwrajka
University of Pennsylvania — Fellow, Department of Rheumatology

Establishing a Spatially–integrated Transcriptomic, Epigenomic, and Histologic Signature of Fibrosis in Systemic Sclerosis

Michael Longaker, MD
Stanford University School of Medicine – Deane P. and Louise Mitchell Professor in the School of Medicine and Professor, by courtesy, of Materials Science and Engineering
Howard Chang, MD, PhD
Stanford University School of Medicine — Professor of Dermatology and of Genetics, Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics
Howard Hughes Medical Institute — Investigator
NIH Center of Excellence in Genomic Science: Center for Personal Dynamic Regulome — Director

Examining Mechanisms of Autonomic Nervous System Dysfunction and GI Disease in Scleroderma

Zsuzsanna McMahan, MD of the UTHealth Houston McGovern School of Medicine
Gabsang Lee of the Johns Hopkins University School of Medicine

Macrophage-stromal Cell Interactions in Tissue Homeostasis and Fibrosis

Ruslan Medzhitov, PhD
Yale School of Medicine — Sterling Professor of Immunobiology
Howard Hughes Medical Institute — Investigator

Identification of Novel Pathogenic Genes in Juvenile Systemic Sclerosis

Kathryn Torok, MD 
Pittsburgh Children’s Hospital — Associate Professor of Medicine

In collaboration with
Dan Kastner, MD, PhD
National Human Genome Research Institute — Scientific Director of the Intramural Program
Elaine Remmers, PhD
National Human Genome Research Institute — Associate Investigator, Inflammatory Disease Section

A Gene Expression Map of Scleroderma

Michael L. Whitfield, PhD
Geisel School of Medicine at Dartmouth — Chair and Professor of Biomedical Data Science; Professor of Molecular and Systems

Multi-omic Profiling of Interstitial Lung Disease in Systemic Sclerosis

Paul Wolters, MD
University of California, San Francisco — Professor of Medicine
Gerlinde Wernig, MD
Stanford University — Assistant Professor of Pathology
Howard Chang, MD, PhD
Stanford University School of Medicine — Professor of Dermatology and of Genetics, Virginia and D. K. Ludwig Professor of Cancer and Genomics and of Genetics
Howard Hughes Medical Institute — Investigator
NIH Center of Excellence in Genomic Science: Center for Personal Dynamic Regulome — Director

Identifying Unique Molecular Profiles of Subtypes of Scleroderma-associated ILD

Paul Wolters, MD
University of California, San Francisco — Professor of Medicine

Identifying and Optimizing Care for Mechanistically-driven, Clinically-relevant Scleroderma Subgroups

Scott Zeger, PhD
Johns Hopkins University School of Medicine — Professor of Biostatistics
Ami Shah, MD, MHS
Johns Hopkins University School of Medicine – Associate Professor of Medicine
Laura Hummers, MD of the Johns Hopkins University School of Medicine
Ji Soo Kim, PhD of the Johns Hopkins University School of Medicine

Spatial Transcriptomics of Skin to Augment Understanding of Cellular Interactions and Disease Propagation in Juvenile Scleroderma

Kathryn Torok, MD 
Pittsburgh Children’s Hospital — Associate Professor of Medicine
Wei Chen, PhD
University of Pittsburgh — Professor of Pediatrics, Biostatistics, and Human Genetics

CRISTAL: Developing the Combined Response Index for Scleroderma Trials Assessing Limited Cutaneous Systemic Sclerosis

Dinesh Khanna, MD, MSc of the University of Michigan and Alain Lescoat, MD of the University Hospital of Rennes