Check out the latest research updates from the wider community from this month. While we didn’t fund these projects, we’re encouraged to see a continued focus on understanding scleroderma.
Plant-based nanoparticle therapy eases skin thickening in SSc: Study
A nanoparticle-based delivery system loaded with kaempferol, a plant compound, reduced skin thickening, inflammation, and fibrosis-related molecules in a mouse model of systemic sclerosis.
Distinct symptom pattern found for triple-negative scleroderma patients
A large registry study found that scleroderma patients negative for all three common disease-associated autoantibodies had higher rates of muscle damage and lung disease, but fewer blood vessel complications, than other patients.
Esophageal Strictures in SSc Linked to Longer Disease Duration and GI Manifestations
A large cohort study found that clinically significant esophageal strictures in systemic sclerosis have become less common and occur later in the disease course, likely reflecting increased use of proton pump inhibitors, with no impact on overall survival.
